- 2003
- - Something's Gotta Give
  - Best Actress
  - Academy Award
- - Something's Gotta Give
  - Best Performance By an Actress in a Motion Picture - Comedy or Musical
  - Golden Globe
- - Something's Gotta Give
  - Outstanding Performance by a Female Actor in a Leading Role
  - Screen Actors Guild Awards
- 1996
- - Marvin's Room
  - Best Actress
  - Academy Award
- - Marvin's Room
  - Outstanding Performance by a Female Actor in a Leading Role
  - Screen Actors Guild Awards
- 1987
- - Baby Boom
  - Best Performance By an Actress in a Motion Picture - Comedy or Musical
  - Golden Globe
- 1982
- - Shoot the Moon
  - Best Performance By an Actress in a Motion Picture - Drama
  - Golden Globe
- - Reds
  - Actress
  - British Academy of Film & Television Arts
- 1981
- - Reds
  - Best Actress
  - Academy Award
- - Reds
  - Best Performance By an Actress in a Motion Picture - Drama
  - Golden Globe
- 1979
- - Manhattan
  - Actress
  - British Academy of Film & Television Arts
- 1977
- - Looking for Mr. Goodbar
  - Best Performance By an Actress in a Motion Picture - Drama
  - Golden Globe
- - Annie Hall
  - Actress
  - British Academy of Film & Television Arts
- - Annie Hall
  - Best Actress
  - Academy Award
- - Annie Hall
  - Best Performance By an Actress in a Motion Picture - Comedy or Musical
  - Golden Globe